Life Sciences 2008-01-01

Anxiolytic-like effect of danshensu [(3-(3,4-dihydroxyphenyl)-lactic acid)] in mice

Guyoung Kwon, Hyun Ji Kim, Se Jin Park, Hyung Eun Lee, Hyun Woo, Young Je Ahn, Qingtao Gao, Jae Hoon Cheong, Dae Sik Jang, Jong Hoon Ryu

文献索引：Life Sci. 101(1-2) , 73-8, (2014)

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摘要

Aims Danshensu [3-(3,4-dihydroxyphenyl)-lactic acid], a phenylpropanoid compound isolated from Prunella vulgaris var. lilacina, is a well-known antioxidant. Although its antioxidant activity and cardioprotective effect have been reported, the pharmacological properties of danshensu in the central nervous system remain unclear. We investigated whether danshensu exerts anxiolytic-like activity in mice.