丹参素 钠盐结构式
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常用名 | 丹参素 钠盐 | 英文名 | Danshensu Sodium Salt |
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| CAS号 | 81075-52-7 | 分子量 | 220.154 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C9H9NaO5 | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
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Cardioprotective effect of paeonol and danshensu combination on isoproterenol-induced myocardial injury in rats.
PLoS ONE 7(11) , e48872, (2012) Traditional Chinese medicinal herbs Cortex Moutan and Radix Salviae Milthiorrhizaeare are prescribed together for their putative cardioprotective effects in clinical practice. However, the rationale of the combined use remains unclear. The present study was d... |
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Simultaneous determination of danshensu, salvianolic acid B, and paeonol in ShuangDan oral liquid by HPLC.
J. AOAC Int. 96(1) , 20-3, (2013) An HPLC-photodiode array detector (PDAD) method was developed for simultaneous determination of danshensu, salvianolic acid B, and paeonol in a traditional Chinese medicinal preparation ShuangDan oral liquid, which is widely used to treat coronary heart disea... |
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[Capillary electrophoresis with field-enhanced stacking for determination of water-soluble active principles in Salvia miltiorrhiza var. miltiorrhiza f. alba].
Zhongguo Zhong Yao Za Zhi 36(11) , 1466-70, (2011) A simple and sensitive capillary electrophoresis method with field-enhanced stacking concentration for the analysis of protocatechuic aldehyde, protocatechuic acid, danshensu, rosmarinic acid and salvianolic acid B in Salvia miltiorrhiza var. miltiorrhiza f. ... |
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Danshensu is the major marker for the antioxidant and vasorelaxation effects of Danshen (Salvia miltiorrhiza) water-extracts produced by different heat water-extractions.
Phytomedicine 19(14) , 1263-9, (2012) Some of the major components of Danshen (Salvia miltiorrhiza), a widely used Chinese herbal medicine rich in phenolic acids, are thermosensitive and may degrade to other phenolic acids during extractions with heating. The chemical profiles of Danshen water-ex... |
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Anxiolytic-like effect of danshensu [(3-(3,4-dihydroxyphenyl)-lactic acid)] in mice
Life Sci. 101(1-2) , 73-8, (2014) Aims Danshensu [3-(3,4-dihydroxyphenyl)-lactic acid], a phenylpropanoid compound isolated from Prunella vulgaris var. lilacina, is a well-known antioxidant. Although its antioxidant activity and cardioprotective effect have been reported, the pharmacological ... |
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The synthesis and biological evaluation of novel Danshensu-cysteine analog conjugates as cardiovascular-protective agents.
Eur. J. Med. Chem. 55 , 176-87, (2012) A series of novel amide and thioester conjugates between Danshensu and cysteine derivatives have been designed and synthesized based on the strategy of "medicinal chemical hybridization". Pharmacological evaluation indicated that the amide conjugates 3a/4a/17... |
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Danshensu ameliorates the cognitive decline in streptozotocin-induced diabetic mice by attenuating advanced glycation end product-mediated neuroinflammation.
J. Neuroimmunol. 245(1-2) , 79-86, (2012) Spatial learning and memory are impaired in diabetic animals. The interaction of advanced glycation end products (AGEs) with the receptor of AGEs (RAGE), resulting in the activation of nuclear factor-κB (NF-κB), plays an important role in pathways leading to ... |
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An effective strategy for the synthesis of biocompatible gold nanoparticles using danshensu antioxidant: prevention of cytotoxicity via attenuation of free radical formation.
Nanotoxicology 7(3) , 294-300, (2013) To suppress the cytotoxicity of gold nanoparticles (AuNPs), danshensu, a naturally occurring polyphenol antioxidant isolated from Chinese herb, was used to provide a fundamental protection layer for AuNPs, to alleviate oxidative stress and as a reducing agent... |
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Neuroprotective effect of Danshensu derivatives as anti-ischaemia agents on SH-SY5Y cells and rat brain.
Biosci. Rep. 33(4) , doi:10.1042/BSR20130032, (2013) Novel Danshensu derivatives (3-8) were designed and synthesized to improve bioactivity based on the strategy of 'medicinal chemical hybridization'. Our previous studies indicated that these compounds exhibited noticeable cardioprotective activities. Here, we ... |
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A simple, but highly sensitive, graphene-based voltammetric sensor for salvianic acid A sodium.
Anal. Sci. 29(6) , 625-30, (2013) A simple, but highly sensitive, electrochemical sensor for the determination of salvianic acid A sodium (SAS) based on reduced graphene oxide (rGO) is reported. The sensor (rGO/GCE(ox)) was prepared by coating an rGO film on the surface of a pre-anodized glas... |