Robust routes for the synthesis of N-acylated-L-homoserine lactone (AHL) quorum sensing molecules with high levels of enantiomeric purity

JT Hodgkinson, WRJD Galloway, M Casoli, H Keane…

文献索引：Hodgkinson, James T.; Galloway, Warren R.J.D.; Casoli, Mariangela; Keane, Harriet; Su, Xianbin; Salmond, George P.C.; Welch, Martin; Spring, David R. Tetrahedron Letters, 2011 , vol. 52, # 26 p. 3291 - 3294

全文：HTML全文

被引用次数: 14

摘要

Abstract The ready availability of native quorum sensing molecules and related structural analogues is of significant biological interest in the development of methods to manipulate bacterial quorum sensing systems in a useful fashion. In this Letter we report robust routes for the synthesis of a range of N-acylated-l-homoserine lactone (AHL) quorum sensing molecules. Crucially, we have analysed the enantiopurity of the final AHLs and in all ...