N-3-Oxo-tetradecanoyl-L-homoserine lactone

• 常用名: N-3-Oxo-tetradecanoyl-L-homoserine lactone
• 英文名: N-3-oxo-tetradecanoyl-L-Homoserine lactone
• CAS号: 177158-19-9
• 分子量: 325.443
• 密度: 1.0±0.1 g/cm3
• 沸点: 537.3±50.0 °C at 760 mmHg
• 分子式: C₁₈H₃₁NO₄
• 熔点: N/A
• 闪点: 278.7±30.1 °C

用途

N-3-氧代-十四烷酰-L-高丝氨酸内酯(Oxo-C14-HSL)是一种根际细菌诱导剂,可以提高对线虫的基本防御能力[1]。

名称

• 英文名: N-3-oxo-tetradecanoyl-L-Homoserine lactone

生物活性

• 描述: N-3-氧代-十四烷酰-L-高丝氨酸内酯(Oxo-C14-HSL)是一种根际细菌诱导剂,可以提高对线虫的基本防御能力[1]。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 细菌
• 靶点实验:

  rhizobacterial[1]

• 体外研究: N-3-氧代-十四烷酰-L-高丝氨酸内酯是一种根际细菌诱导剂。N-3-氧代-十四烷酰-L-高丝氨酸可以改善对线虫的基本防御[1]。
• 参考文献:

  [1]. Adss S, et al. Priming Soybean cv. Primus Leads to Successful Systemic Defense Against the Root-Lesion Nematode, Pratylenchus penetrans. Front Plant Sci. 2021;12:651943. Published 2021 May 12.

物理化学性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 537.3±50.0 °C at 760 mmHg
• 分子式: C₁₈H₃₁NO₄
• 分子量: 325.443
• 闪点: 278.7±30.1 °C
• 精确质量: 325.225311
• PSA: 72.47000
• LogP: 3.08
• InChIKey: YQFJJDSGBAAUPW-INIZCTEOSA-N
• SMILES: CCCCCCCCCCCC(=O)CC(=O)NC1CCOC1=O
• 蒸汽压: 0.0±1.4 mmHg at 25°C
• 折射率: 1.484

靶点实验

查看更多实验

实验名称：Agonist activity at Pseudomonas aeruginosa LasR cognate receptor expressed in Escheri... 来源：ChEMBL 靶标：Transcriptional activator protein LasR External Id：CHEMBL1827923

实验名称：Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：HCMV UL50 External Id：HMS1262

实验名称：Induction of apoptosis in P388D1 cell line 来源：ChEMBL 靶标：P388 External Id：CHEMBL868941

实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：Stabilization of p53 in human papillomavirus-positive cells 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：Cellular tumor antigen p53 External Id：HMS1485

实验名称：Agonist activity at Pseudomonas aeruginosa LasR receptor expressed in Escherichia col... 来源：ChEMBL 靶标：Transcriptional activator protein LasR External Id：CHEMBL1827921

实验名称：Discovering small molecule activators of G protein-gated inwardly-rectifying potassiu... 来源：15621 靶标：G protein-activated inward rectifier potassium channel 2 External Id：VANDERBILT_HTS_GIRK2_MPD

实验名称：Inhibition of murine splenocyte proliferation 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL748462

实验名称：A screen for small molecules that modulate mitochondrial supercomplex formation 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1482

实验名称：Agonist activity at Pseudomonas aeruginosa QscR expressed in Escherichia coli assesse... 来源：ChEMBL 靶标：LuxR family transcriptional regulator External Id：CHEMBL925888

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英文别名

• 3-Oxo-N-[(3S)-2-oxotetrahydro-3-furanyl]tetradecanamide
• N-benzoyl-1-amino-3-propanal
• 3-benzamidopropanal