Bioorganic & Medicinal Chemistry Letters 2010-11-15

Synthesis and antifungal activity of benzofuran-5-ols.

Chung-Kyu Ryu, Ae Li Song, Jung Yoon Lee, Jung An Hong, Joo Hee Yoon, Aram Kim, Chung-Kyu Ryu, Ae Li Song, Jung Yoon Lee, Jung An Hong, Joo Hee Yoon, Aram Kim

文献索引：Bioorg. Med. Chem. Lett. 20 , 6777-80, (2010)

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摘要

Benzofuran-5-ol derivatives were synthesized and tested for in vitro antifungal activity against Candida, Aspergillus species, and Cryptococcus neoformans. Among them tested, many benzofuran-5-ols showed good antifungal activity. The results suggest that benzofuran-5-ols would be promising antifungal agents.Copyright © 2010 Elsevier Ltd. All rights reserved.