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Development of Pharmaceutical Drugs, Drug Intermediates and Ingredients by Using Direct Organo??Click Reactions

DB Ramachary, M Kishor…

文献索引:Ramachary, Dhevalapally B.; Kishor, Mamillapalli; Reddy, Y. Vijayendar European Journal of Organic Chemistry, 2008 , # 6 p. 975 - 993

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被引用次数: 28

摘要

Abstract Here we report on our studies of the use of combinations of amino acids, amines, K 2 CO 3 or Cs 2 CO 3 and CuSO 4/Cu for catalysing green cascade reactions. We aimed to prepare the highly reactive and substituted olefin species 7 and 8, under very mild and environmentally friendly conditions, thus giving the hydrogenated products 10 and 12 through the action of Hantzsch ester (4) by self-catalysis through decreasing the HOMO– ...