Evaluations of the comparative efficacy and safety of a newly developed emollient ointment formulation of hydrocortisone valerate 0.2 percent were made in two double-blind, multicenter trials involving 145 patients with atopic dermatitis. Data are presented which indicate that hydrocortisone valerate 0.2 percent ointment is effective in the treatment of mild to moderate atopic dermatitis, has efficacy comparable to that of other intermediate potency corticosteroid ointments, and, moreover, that it is readily accepted by patients.