前往化源商城

Organic Letters 2001-07-12

Total synthesis of epothilones B and D.

R E Taylor, Y Chen

文献索引:Org. Lett. 3(14) , 2221-4, (2001)

全文:HTML全文

摘要

[reaction: see text] A highly convergent total synthesis of the natural products epothilone B and D is described. The route is highlighted by efficient generation of a C12-C13 trisubstituted olefin which exploits a sequential Nozaki-Hiyama-Kishi coupling and a stereoselective thionyl chloride rearrangement.

相关化合物

结构式 名称/CAS号 全部文献
6-Hept炔酸 结构式 6-Hept炔酸
CAS:30964-00-2