Facile and regioselective dealkylation of alkyl aryl ethers using niobium (V) pentachloride

Y Sudo, S Arai, A Nishida

文献索引：Sudo, Yukinori; Arai, Shigeru; Nishida, Atsushi European Journal of Organic Chemistry, 2006 , # 3 p. 752 - 758

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被引用次数: 21

摘要

Abstract A simple and facile method for the cleavage of carbon–oxygen bonds promoted by niobium pentachloride (V) is described. Excellent yields and regioselectivities were observed with various alkyl aryl ethers to give the phenols. NMR studies revealed the formation of monoaryloxy niobium salt (V), and a neighboring-group effect may play a significant role in the regioselectivity.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 ...