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MK-7655

更新时间:2024-09-16 12:43:43

常用名 瑞来巴坦 CAS号 1174018-99-5
价格 ¥需询单/25g ¥需询单/10g 纯度 98.0%
备货期 需询单 库存 询单
 产品详情(用途,包装等)
用途:
Relebactam is a diazabicyclooctane inhibitor with activity against a wide spectrum of β-lactamases, including class A (extended-spectrum β-lactamases [ESBLs] and KPC) and class C (AmpC) enzymes.Target: beta-lactamaseImipenem with Relebactam is active against Escherichia coli, Klebsiella pneumoniae, and Enterobacter spp., including K. pneumoniae carbapenemase (KPC)-producing isolates. The combination of Imipenem with Relebactam demonstrated activity against KPC-producing Enterobacteriaceae and multidrug-resistant P. aeruginosa. The imipenem MIC50 and MIC90 values for the ESBL-producing isolates were 0.25 and 0.5 μg/ml, respectively; with the addition of Relebactam, the corresponding values were 0.25 and 0.25 μg/ml. Five isolates harbored blaKPC. For these 5 isolates, the imipenem MICs ranged from 0.5 to >32 μg/ml. With the addition of Relebactam, the MICs decreased to 0.12 to 0.5 μg/ml.[1] Relebactam inhibits most class A and class C β-lactamases, with selected inhibition of class D enzymes by avibactam. β-Lactamase inhibitors (BLIs) have played an important role in combatting β-lactam resistance in Gram-negative bacteria, but their effectiveness has diminished with the evolution of diverse and deleterious varieties of β-lactamases.[2]
物理化学性质:
CAS号:1174018-99-5
常用中文名:瑞来巴坦
常用英文名:Relebactam
分子式:C12H20N4O6S
分子量:348.37500
密度:N/A
沸点:N/A
熔点:N/A
闪点:N/A
储存条件:2-8℃

供应商信息

上海禹犇生物科技有限公司

认证状态:未认证供应商
电话:+8621-61350663
地址:上海市奉贤区星火开发区莲塘路251号14幢20521室
地区: 上海市 上海市 奉贤区
联系人:丁先生
联系人电话:+86-15502154572
邮件:yuben012@sina.com
网址:https://www.chemsrc.com/saler/11152.html
主要市场:
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主要合作伙伴:
上海禹犇生物科技有限公司是集医药化学品(含中间体)、精细化学品和生物医药产品的研究、开发、生产、产品销售、技术服务于一体的高新企业。
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参考价格:$460/10mM*1mLinWater
其他供应商价格:
2022-03-04 Relebactam
价格:¥1536.9
2024-07-15 硫酸单((1R,2S,5R)-7-氧代-2-(哌啶-4-基氨基甲酰基)-1,6-二氮杂双环[3.2.1]辛-6-基)酯
价格:需询单
2023-11-18 Relebactam
价格:¥需询单
2021-04-03 MK-7655
价格:¥8120.0
2022-05-12 Relebactam
价格:$需询单
2023-09-27 MK7655
价格:¥需询单
2021-05-13 瑞来巴坦(Relebactam)
价格:¥需询单
2024-02-05 瑞来巴坦
价格:¥需询单

查看所有价格,请点击瑞来巴坦价格