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奈妥吡坦

更新时间:2025-09-01 21:01:48

常用名 奈妥匹坦 CAS号 290297-26-6
价格 ¥需询单/1kg 纯度 99.0%
备货期 需询单 库存 现货
 产品详情(用途,包装等)
用途:
Netupitant (CID-6451149) is a highly potent and selective, orally active neurokinin-1 receptor antagonist with Ki of 0.95 nM.IC50 value: 0.95 nM (Ki) [1]Target: NK1 receptorin vitro: Netupitant also dose-dependently inhibited the SP response as expected from an NK1 receptor antagonist. Importantly, when both palonosetron and netupitant were present, they exhibited an enhanced inhibition of the SP response compared to either of the two antagonists alone [2].in vivo: In mice the intrathecal injection of SP elicited the typical scratching, biting and licking response that was dose-dependently inhibited by Netupitant given intraperitoneally in the 1-10mg/kg dose range. In gerbils, foot tapping behavior evoked by the intracerebroventricular injection of a NK(1) agonist was dose-dependently counteracted by Netupitant given intraperitoneally (ID(50) 1.5mg/kg) or orally (ID(50) 0.5mg/kg) [3].
物理化学性质:
CAS号:290297-26-6
常用中文名:奈妥匹坦
常用英文名:Netupitant
分子式:C30H32F6N4O
分子量:578.592
密度:1.3±0.1 g/cm3
沸点:597.4±50.0 °C at 760 mmHg
熔点:N/A
闪点:315.1±30.1 °C
储存条件:-20℃

供应商信息

上海米修化工有限公司

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地址:上海金山漕泾镇亭卫公路
地区: 上海市 上海市 浦东新区
联系人:张海燕
联系人电话:18101936766
邮件:eileen@shmychem.com
网址:http://www.shmychem.com/
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参考价格:$76/10mM*1mLinDMSO
其他供应商价格:
2024-03-12 奈妥吡坦
价格:¥3089.9
2024-09-13 奈妥吡坦
价格:¥需询单
2021-02-06 Netupitant
价格:¥937.0
2021-05-10 奈妥吡坦
价格:¥需询单
2017-09-08 2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridin-3-yl]propanamide
价格:¥需询单
2017-07-06 奈妥吡坦NE-IMP6
价格:¥需询单
2024-01-09 NETUPITANT
价格:$需询单

查看所有价格,请点击奈妥匹坦价格