UNC1215
更新时间：2018-04-15 07:24:50
| 常用名 | 1,1'-[2-(苯基氨基)-1,4-亚苯基]二[1-[4-(1-吡咯烷基)-1-哌啶基]甲酮] | CAS号 | 1415800-43-9 |
|---|---|---|---|
| 价格 | ￥需询单/1kg | 纯度 | 99.0% |
| 备货期 | 7天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： UNC1215 is a potent and selective chemical probe for the methyllysine (Kme) reading function of L3MBTL3 with Kd value of 120 nM.IC50 Value: 120 nM (Kd) [1]Target: L3MBTL3 In vitro: UNC1215 binds L3MBTL3 with a K(d) of 120 nM, competitively displacing mono- or dimethyllysine-containing peptides, and is greater than 50-fold more potent toward L3MBTL3 than other members of the MBT family while also demonstrating selectivity against more than 200 other reader domains examined. X-ray crystallography identified a unique 2:2 polyvalent mode of interaction between UNC1215 and L3MBTL3. In cells, UNC1215 is nontoxic and directly binds L3MBTL3 via the Kme-binding pocket of the MBT domains. UNC1215 increases the cellular mobility of GFP-L3MBTL3 fusion proteins, and point mutants that disrupt the Kme-binding function of GFP-L3MBTL3 phenocopy the effects of UNC1215 on localization [1]. 物理化学性质： CAS号：1415800-43-9 常用中文名：1,1'-[2-(苯基氨基)-1,4-亚苯基]二[1-[4-(1-吡咯烷基)-1-哌啶基]甲酮] 常用英文名：UNC1215 分子式：C32H43N5O2 分子量：529.716 密度：1.2±0.1 g/cm3 沸点：712.1±60.0 °C at 760 mmHg 熔点：N/A 闪点：384.5±32.9 °C 储存条件：2-8°C |
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：UNC1215
- 价格： ￥978.9/10mg ￥5767.9/100mg ￥12977.9/250mg ￥2059.9/25mg
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
查看所有供应商和价格请点击：
1,1'-[2-(苯基氨基)-1,4-亚苯基]二[1-[4-(1-吡咯烷基)-1-哌啶基]甲酮]生产厂家
参考价格：$112/10mM*1mLinDMSO