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匹可硫酸钠

更新时间:2023-10-01 23:49:55

常用名 匹可硫酸钠 CAS号 10040-45-6
价格 ¥需询单/25kg 纯度 98.0%
备货期 需询单 库存 询单
 产品详情(用途,包装等)
用途:
Sodium Picosulfate inhibits absorption of water and electrolytes, and increases their secretion.Target: OthersSodium Picosulfate displays cytotoxic effects on cultured liver cells. 800 and 1600 mg/mL induces dose-dependently vacuolic and fatty change as well as necrosis combined with a lowered mitotic activity and a slight increase in LDH values of the rapidly growing cultured liver cells of rabbit. Comparable but less severe effects are observed in 4-day old liver cell cultures of rat, while liver cells cultured for 6 to 11 days tolerate 1600 mg/mL Sodium Picosulfate. In human liver cultures the number of cells is slightly lowered at 800 and 1600 mg/mL and the number of nuclei in division is decreased dependent on dose [1]. Sodium Picosulphate has no major influence on ileal and colonic epithelial cell proliferation. In a 12 weeks study, 10 mg/kg Sodium Picosulphate continuously treatment does not influence the labeling index of Brdu (LI) in the ileum and induces no statistically significant increase of the LI when the treated groups are compared with the control group. The proliferative pattern along the crypts remains unchanged with sodium picosulphate treatment throughout the study [2]. Sodium Picosulphate does not induce chronic changes in colonic motility in rats under long-term treatment. 10mg/kg/day Sodium Picosulphate pretreated for 23 weeks does not induce any significant change in the duration of long spike bursts (LSB) which are associated with phasic contractions, or in LSB frequency in the fasted state or after a 3-gram meal [3].
物理化学性质:
CAS号:10040-45-6
常用中文名:匹可硫酸钠
常用英文名:sodium picosulfate
分子式:C18H13NNa2O8S2.H2O
分子量:499.42
密度:N/A
沸点:N/A
熔点:272 - 275ºC
闪点:N/A
储存条件:Hygroscopic, Refrigerator, Under Inert Atmosphere

供应商信息

广州佰瑞医药有限公司

认证状态:未认证供应商
电话:020-37651955
地址:广州市海珠区新港中路397号自编76、77号B4-02
地区: 广东省 广州市 海珠区
联系人:刘鹏虎
联系人电话:18028682016
邮件:dylan@gzbr.com.cn
网址:http://www.gzbr.com.cn/
主要市场:
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主要合作伙伴:
佰瑞医药成立于2001年,是一家具GSP资质、以医药原料进出口、药品进口注册、一致性评价服务、原研参比制剂、PEG及其衍生物、BIA整体分离柱等为主要业务模块的医药产品供应链服务企业,秉持“诚信、专业、信任、高效”的经营理念及以“让世界爱上药品‘中国制造’”的使命,致力于推动药品“中国制造” 国际化,持续服务于国内的医药企业,将更多、更高性价比的优质产品和技术服务输送到中国。公司是多家国外知名药企在中国的授权总代理,拥有专业、高效的市场营销团队、技术团队和注册团队,团队成员均拥有药学相关专业背景,具丰富的国内外资源和网络,能够在业务开拓、采购销售、物流仓储、技术支持等环节给予客户最快速、最专业的一站式解决方案。
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  • 中山星瑞化工有限公司
  • 广东省 中山市 中山火炬高技术产业开发区
  • 产品名:匹可硫酸钠
  • 价格: ¥需询单/25kg
  • 纯度:99.0%
  • 备货期:需询单
  • 联系人:王经理
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