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Sodium picosulfate

更新时间:2024-01-28 11:38:04 采购访问:40次

常用名 匹可硫酸钠 CAS号 10040-45-6
价格 ¥需询单/1g 纯度 98.0%
备货期 1天 库存 现货
 产品详情(用途,包装等)
用途:
Sodium Picosulfate inhibits absorption of water and electrolytes, and increases their secretion.Target: OthersSodium Picosulfate displays cytotoxic effects on cultured liver cells. 800 and 1600 mg/mL induces dose-dependently vacuolic and fatty change as well as necrosis combined with a lowered mitotic activity and a slight increase in LDH values of the rapidly growing cultured liver cells of rabbit. Comparable but less severe effects are observed in 4-day old liver cell cultures of rat, while liver cells cultured for 6 to 11 days tolerate 1600 mg/mL Sodium Picosulfate. In human liver cultures the number of cells is slightly lowered at 800 and 1600 mg/mL and the number of nuclei in division is decreased dependent on dose [1]. Sodium Picosulphate has no major influence on ileal and colonic epithelial cell proliferation. In a 12 weeks study, 10 mg/kg Sodium Picosulphate continuously treatment does not influence the labeling index of Brdu (LI) in the ileum and induces no statistically significant increase of the LI when the treated groups are compared with the control group. The proliferative pattern along the crypts remains unchanged with sodium picosulphate treatment throughout the study [2]. Sodium Picosulphate does not induce chronic changes in colonic motility in rats under long-term treatment. 10mg/kg/day Sodium Picosulphate pretreated for 23 weeks does not induce any significant change in the duration of long spike bursts (LSB) which are associated with phasic contractions, or in LSB frequency in the fasted state or after a 3-gram meal [3].
物理化学性质:
CAS号:10040-45-6
常用中文名:匹可硫酸钠
常用英文名:sodium picosulfate
分子式:C18H13NNa2O8S2.H2O
分子量:499.42
密度:N/A
沸点:N/A
熔点:272 - 275ºC
闪点:N/A
储存条件:Hygroscopic, Refrigerator, Under Inert Atmosphere

供应商信息

武汉敬康恩生物医药科技有限公司 认证供应商

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参考价格:$66/10mM*1mLinDMSO
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