| 常用名 | (±)-bay-1251152 | CAS号 | 1610358-53-6 |
|---|---|---|---|
| 价格 | $550.0/50mg | 纯度 | 98.0% |
| 备货期 | 1天 | 库存 | 3 |
| 产品网页 | https://www.dcchemicals.com/product_show-DC60039.html | ||
| 产品详情(用途,包装等)
AY-1251152 is a potent and highly selective PTEF/CDK9 inhibitor. BAY1251152 binds to and blocks the phosphorylation and kinase activity of CDK9, thereby preventing PTEFb-mediated activation of RNA Pol II and leading to the inhibition of gene transcription of various anti-apoptotic proteins. This may cause cell cycle arrest and induce apoptosis, which may lead to a reduction in tumor cell proliferation. |