(±)-BAY-1251152
Published date: 2020-10-20 11:19:40
|
Name | (±)-BAY-1251152 | CAS# | 1610358-53-6 |
|---|---|---|---|---|
| Price | $550.0/50mg | Purity | 98.0% | |
| Stocking Period |
1 Day | Stock | 3 | |
| Product Webpage: | https://www.dcchemicals.com/product_show-DC60039.html | |||
| Detail
Product Information
AY-1251152 is a potent and highly selective PTEF/CDK9 inhibitor. BAY1251152 binds to and blocks the phosphorylation and kinase activity of CDK9, thereby preventing PTEFb-mediated activation of RNA Pol II and leading to the inhibition of gene transcription of various anti-apoptotic proteins. This may cause cell cycle arrest and induce apoptosis, which may lead to a reduction in tumor cell proliferation. |
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