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卡比吗唑

更新时间:2025-09-21 10:54:16

常用名 卡比吗唑 CAS号 22232-54-8
价格 ¥需询单/1mg 纯度 98.0%
备货期 3天 库存 现货
 产品详情(用途,包装等)
用途:
Carbimazole is an imidazole antithyroid agent. Target: OthersCarbimazole is an effective thyroid hormone inhibitor under a class of drugs known as pro-drugs. It is considered a pro-drug because it converts to methimazole after being absorbed by the body, generating an antithyroid action that works against hyperthyroidism (excessive production of thyroid hormones) and thyrotoxicosis (inflammation of the thyroid gland) [1]. Methimazole prevents the thyroid peroxidase enzyme from coupling and iodinating the tyrosine residues on thyroglobulin, hence reducing the production of the thyroid hormones T3 and T4 (thyroxine) [2].Carbimazole (CBZ) is one of the major drugs currently used for the treatment of Graves' disease. Experiments with [35S] CBZ in rats showed that the drug is so rapidly transformed to MMI after i.v. injection (within 3 min) that very little of the unchanged drug would be expected to reach the thyroid gland. The antithyroid action of CBZ in rats, therefore, can be ascribed entirely to the MMI to which it is rapidly converted [3].
物理化学性质:
CAS号:22232-54-8
常用中文名:卡比吗唑
常用英文名:Carbimazole
分子式:C7H10N2O2S
分子量:186.232
密度:1.3±0.1 g/cm3
沸点:240.4±23.0 °C at 760 mmHg
熔点:124°C
闪点:99.2±22.6 °C
储存条件:Refrigerator

供应商信息

上海泽涵生物医药科技有限公司

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电话:021-61350663
地址:上海浦东新区丽正路1628号4幢4045室
地区: 上海市 上海市 浦东新区
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联系人电话:13052117465
邮件:sales@zehanbiopharma.com
网址:http://www.zehanbiopharma.com
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上海泽涵生物医药科技有限公司是集医药化学品(含中间体)、精细化学品和生物医药产品的研究、开发、生产、产品销售、技术服务于一体的高新企业。
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参考价格:$75/10mM*1mLinDMSO
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