3-甲基-2-硫代咪唑啉-1-羧酸乙酯
更新时间：2024-07-15 12:33:48
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| 常用名 | 卡比吗唑 | CAS号 | 22232-54-8 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： Carbimazole is an imidazole antithyroid agent. Target: OthersCarbimazole is an effective thyroid hormone inhibitor under a class of drugs known as pro-drugs. It is considered a pro-drug because it converts to methimazole after being absorbed by the body, generating an antithyroid action that works against hyperthyroidism (excessive production of thyroid hormones) and thyrotoxicosis (inflammation of the thyroid gland) [1]. Methimazole prevents the thyroid peroxidase enzyme from coupling and iodinating the tyrosine residues on thyroglobulin, hence reducing the production of the thyroid hormones T3 and T4 (thyroxine) [2].Carbimazole (CBZ) is one of the major drugs currently used for the treatment of Graves' disease. Experiments with [35S] CBZ in rats showed that the drug is so rapidly transformed to MMI after i.v. injection (within 3 min) that very little of the unchanged drug would be expected to reach the thyroid gland. The antithyroid action of CBZ in rats, therefore, can be ascribed entirely to the MMI to which it is rapidly converted [3]. 物理化学性质： CAS号：22232-54-8 常用中文名：卡比吗唑 常用英文名：Carbimazole 分子式：C7H10N2O2S 分子量：186.232 密度：1.3±0.1 g/cm3 沸点：240.4±23.0 °C at 760 mmHg 熔点：124°C 闪点：99.2±22.6 °C 储存条件：Refrigerator |
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- 产品名：3-甲基-2-硫代咪唑啉-1-羧酸乙酯
- 价格：
- 纯度：98.0%
- 备货期：10天
- 联系人：徐经理
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参考价格：$75/10mM*1mLinDMSO