Lycorine hydrochloride
更新时间：2022-03-08 08:15:23
采购访问：32次
| 常用名 | 盐酸石蒜碱 | CAS号 | 2188-68-3 |
|---|---|---|---|
| 价格 | $需询单/100g $需询单/1kg $需询单/100kg $需询单/1000kg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： Lycorine (hydrochloride) is VE-cadherin inhibitor,and has IC50 of 1.2μM in Hey1B cell.IC50: 1.2μM (Hey1B cell)[2]In vitro:Lycorine (hydrochloride) executed an anti-melanoma vasculogenic effect by inhibiting VE-cadherin gene expression in C8161 cells and caused a decrease in cell surface exposure of VE-cadherin protein. Consistently, LH significantly suppressed VE-cadherin gene promoter activity. [1]Lycorine (hydrochloride) effectively inhibited mitotic proliferation of Hey1B cells (half maximal inhibitory concentration = 1.2 μM) with very low toxicity, resulting in cell cycle arrest at the G2/M transition through enhanced expression of the cell cycle inhibitor p21 and marked down-regulation of cyclin D3 expression. Moreover, LH suppressed both the formation of capillary-like tubes by Hey1B cells cultured in vitro.[2]In vivo: Lycorine effectively suppressed C8161 cell-dominant tumor formation and generation of tumor blood vessels in vivo with low toxicity.[1]Lycorine (hydrochloride) suppressed the formation of the ovarian cancer cell-dominant neovascularization in vivo when administered to Hey1B-xenotransplanted mice, suggest that LH selectively inhibits ovarian cancer cell proliferation and neovascularization and is a potential drug candidate for anti-ovarian cancer therapy.[2] 物理化学性质： CAS号：2188-68-3 常用中文名：盐酸石蒜碱 常用英文名：Lycorine chloride 分子式：C16H18ClNO4 分子量：323.77 密度：N/A 沸点：477.4ºC at 760 mmHg 熔点：210-212ºC 闪点：242.5ºC 储存条件：2-8°C |
达阳化工（杭州）有限公司
认证状态：已认证供应商
商品数：50181件
电话：+86571-88938639
地址：浙江省杭州市西湖区文三路259号2栋9楼
地区： 浙江省 杭州市 西湖区
联系人：王小姐
联系人电话：+86-571-8893-8639
邮件：enquiry@dycnchem.com
网址：http://www.dycnchem.com
主要市场：Mainly in Southeast Asia and European and American markets
年贸易额：10 to 20 million USD
外贸占销售比例：90%
主要合作伙伴：
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：盐酸石蒜碱
- 价格： ￥396.9/1g ￥823.9/100mg ￥205.9/20mg ￥1812.9/250mg
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
- 上海阿摩尔生物科技有限公司
- 上海市 上海市 奉贤区
- 产品名：盐酸石蒜碱
- 价格： ￥需询单/100mg ￥需询单/10mg ￥需询单/1g ￥需询单/250mg
- 纯度：99.0%
- 备货期：需询单
- 联系人：王汐瑶
- 广东翁江化学试剂有限公司
- 广东省 韶关市 翁源县
- 产品名：盐酸石蒜碱
- 价格： ￥960.0/5g
- 纯度：99.0%
- 备货期：需询单
- 联系人：朱丽丹
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参考价格：$66/10mM*1mLinDMSO