| 常用名 | 4'-C-迭氮基胞嘧啶核苷 2',3',5'-三异丁酸酯 | CAS号 | 690270-29-2 |
|---|---|---|---|
| 价格 | $需询单/100g $需询单/1kg $需询单/100kg $需询单/1000kg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情(用途,包装等)
用途: Balapiravir (R1626, Ro 4588161) is the prodrug of a nucleoside analogue inhibitor of the hepatitis C virus (HCV) RNA-dependent RNA polymerase (R1479, RG1479).IC50 Value: Target: HCVBalapiravir(R-1626; R 1626; Ro 4588161) is useful for Anti HCV. Balapiravir (R1626) is the tri-isobutyrate ester prodrug of R1479 under clinical development to improve exposure of R1479 upon oral administration. Balapiravir was discontinued for safety reasons in 28-36% of patients (most often for lymphopenia) and the percentage of patients with serious adverse events (especially hematological, infection, ocular events) was dose related. Serious hematological adverse events (particularly neutropenia, lymphopenia) were more common in balapiravir recipients. Two deaths in the balapiravir/peginterferon alfa-2a/ribavirin combination groups were considered possibly related to study medication. 物理化学性质: CAS号:690270-29-2 常用中文名:4'-C-迭氮基胞嘧啶核苷 2',3',5'-三异丁酸酯 常用英文名:Balapiravir 分子式:C21H30N6O8 分子量:494.49800 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A 储存条件:2-8℃ |