前往化源商城

sodium 5-(aminosulphonyl)-4-chloro-2-(furan-2-ylmethyl)anthranilate

更新时间:2024-04-09 19:26:15 采购访问:34次

常用名 呋塞米钠 CAS号 41733-55-5
价格 $需询单/100g $需询单/1kg $需询单/100kg $需询单/1000kg 纯度 98.0%
备货期 需询单 库存 询单
 产品详情(用途,包装等)
用途:
Furosemide sodium (Lasix) is a loop diuretic inhibitor of Na+/2Cl-/K+ (NKCC) cotransporter of which used in the treatment of congestive heart failure and edema.Target: NKCC Furosemide (INN/BAN) or frusemide is a loop diuretic used in the treatment of congestive heart failure and edema. It is most commonly marketed by Sanofi under the brand name Lasix, and also under the brand names Fusid and Frumex. It has also been used to prevent Thoroughbred and Standardbred race horses from bleeding through the nose during races.Along with some other diuretics, furosemide is also included on the World Anti-Doping Agency's banned drug list due to its alleged use as a masking agent for other drugs.Furosemide, like other loop diuretics, acts by inhibiting NKCC2, the luminal Na-K-2Cl symporter in the thick ascending limb of the loop of Henle. The action on the distal tubules is independent of any inhibitory effect on carbonic anhydrase or aldosterone; it also abolishes the corticomedullary osmotic gradient and blocks negative, as well as positive, free water clearance.Because of the large NaCl absorptive capacity of the loop of Henle, diuresis is not limited by development of acidosis, as it is with the carbonic anhydrase inhibitors. Additionally, furosemide is a noncompetitive subtype-specific blocker of GABA-A receptors. Furosemide has been reported to reversibly antagonize GABA-evoked currents of α6β2γ2 receptors at ?M concentrations, but not α1β2γ2 receptors. During development, the α6β2γ2 receptor increases in expression in cerebellar granule neurons, corresponding to increased sensitivity to furosemide
物理化学性质:
CAS号:41733-55-5
常用中文名:呋塞米钠
常用英文名:Furosemide (sodium)
分子式:C12H10ClN2NaO5S
分子量:352.72600
密度:N/A
沸点:582.1ºC at 760 mmHg
熔点:206ºC
闪点:305.9ºC
储存条件:2-8℃

供应商信息

达阳化工(杭州)有限公司 认证供应商

认证状态:已认证供应商
商品数:50181件
电话:+86571-88938639
地址:浙江省杭州市西湖区文三路259号2栋9楼
地区: 浙江省 杭州市 西湖区
联系人:王小姐
联系人电话:+86-571-8893-8639
邮件:enquiry@dycnchem.com
网址:http://www.dycnchem.com
主要市场:Mainly in Southeast Asia and European and American markets
年贸易额:10 to 20 million USD
外贸占销售比例:90%
主要合作伙伴:
推荐生产厂家/供应商:我要出现这里


查看所有供应商和价格请点击:

呋塞米钠生产厂家


参考价格:$60/1g
其他供应商价格:
2024-07-15 Furosemide sodium?
价格:需询单
2022-09-23 呋塞米钠
价格:¥1000.0
2024-03-12 呋塞米钠
价格:¥269.9

查看所有价格,请点击呋塞米钠价格