| 常用名 | JX06 | CAS号 | 729-46-4 |
|---|---|---|---|
| 价格 | $需询单/100g $需询单/1kg $需询单/100kg $需询单/1000kg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情(用途,包装等)
用途: JX-06 is a potent and selective pyruvate dehydrogenase kinase (PDK) 1/2/3 inhibitor (IC50 values are 28, 49 and 313 nM for PDK2, PDK1 and PDK3, respectively). JX06 Selectively Inhibits Pyruvate Dehydrogenase Kinase PDK1 by a Covalent Cysteine Modification. JX06, as a selective covalent inhibitor of PDK1 in cells, forms a disulfide bond with the thiol group of a conserved cysteine residue (C240) based on recognition of a hydrophobic pocket adjacent to the ATP pocket of the PDK1 enzyme. 物理化学性质: CAS号:729-46-4 常用中文名:JX06 常用英文名:JX 06 分子式:C10H16N2O2S4 分子量:324.50600 密度:1.463g/cm3 沸点:466.3ºC at 760 mmHg 熔点:N/A 闪点:235.8ºC 储存条件:-20℃,惰性气体保存 |