Edoxaban Tosylate Monohydrate
更新时间：2025-08-27 01:17:06
| 常用名 | 伊多塞班对甲苯磺酸盐 | CAS号 | 480449-71-6 |
|---|---|---|---|
| 价格 | ￥需询单/100g ￥需询单/1kg ￥需询单/10kg ￥需询单/25kg | 纯度 | 98.0% |
| 备货期 | 7天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke preventionIC50 Value:Target: factor XaEdoxaban is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention in patients with atrial fibrillation, an elderly population that frequently receives aspirin (ASA) and/or nonsteroidal anti-inflammatory drugs for concurrent illnesses[1].in vitro: Edoxaban PK was not affected by concomitant low-dose ASA or naproxen, but high-dose ASA increased systemic exposure of edoxaban by approximately 30%. The effects of edoxaban on prothrombin time, activated partial thromboplastin time, international normalized ratio, anti-FXa, and intrinsic FXa activity were not influenced by administration with ASA or naproxen. Inhibition of platelet aggregation by high-dose ASA, low-dose ASA, or naproxen was not affected by edoxaban[1].in vivo: Forty-eight subjects, aged 18 to 45 years, received either edoxaban 60 mg once daily × 7 days (n = 24) or digoxin 0.25 mg twice daily × 2 days and once daily × 5 days (n = 24) and then concomitantly for 7 days. Serial blood and urine samples were collected for digoxin and edoxaban concentrations on days 7 and 14. Serial coagulation assays were measured for edoxaban on days 7 and 14. Edoxaban PK parameters demonstrated mild increases in area under the curve and peak concentrations of 9.5% and 15.6%, respectively[2],Clinical trial: Pharmacokinetics, biotransformation, and mass balance of edoxaban, a selective, direct factor Xa inhibitor, in humans was reported[3]. 物理化学性质： CAS号：480449-71-6 常用中文名：伊多塞班对甲苯磺酸盐 常用英文名：edoxaban tosylate 分子式：C31H38ClN7O7S2 分子量：720.259 密度：N/A 沸点：N/A 熔点：N/A 闪点：N/A 储存条件：2-8℃ |
- 上海源溪生物科技有限公司
- 上海市 上海市 浦东新区
- 产品名：Edoxaban
- 价格： ￥需询单/1g
- 纯度：98.9%
- 备货期：1天
- 联系人：赖经理
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：依度沙班对甲苯磺酸盐
- 价格： ￥499.9/5mg ￥3999.9/100mg ￥699.9/10mg ￥2499.9/50mg
- 纯度：99.0%
- 备货期：1天
- 联系人：阿拉丁
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参考价格：$90/5mg