伊多塞班对甲苯磺酸盐

更新时间：2025-08-26 18:17:38

伊多塞班对甲苯磺酸盐结构式	常用名	伊多塞班对甲苯磺酸盐	英文名	edoxaban tosylate
	CAS号	480449-71-6	分子量	720.259
	密度	N/A	沸点	N/A
	分子式	C₃₁H₃₈ClN₇O₇S₂	熔点	N/A
	MSDS	N/A	闪点	N/A

伊多塞班对甲苯磺酸盐用途

Edoxaban(DU-176)是口服的FXa抑制剂,临床开发用于中风预防。

中文名	伊多塞班对甲苯磺酸盐
英文名	edoxaban tosylate
中文别名	甲苯磺酸依度沙班 \| 依度沙班对甲苯磺酸盐
英文别名	更多

描述	Edoxaban(DU-176)是口服的FXa抑制剂,临床开发用于中风预防。
相关类别	信号通路 >> 代谢酶/蛋白酶 >> 因子Xa 研究领域 >> 心血管疾病
参考文献	[1]. Mendell J, Lee F, Chen S, The Effects of the Antiplatelet Agents, Aspirin and Naproxen, on Pharmacokinetics and Pharmacodynamics of the Anticoagulant Edoxaban, a Direct Factor Xa Inhibitor. J Cardiovasc Pharmacol. 2013 Apr 23. [Epub ahead of print] [2]. Mendell J, Noveck RJ, Shi M. Pharmacokinetics of the direct factor Xa inhibitor edoxaban and digoxin administered alone and in combination. J Cardiovasc Pharmacol. 2012 Oct;60(4):335-41. [3]. Bathala MS, Masumoto H, Oguma T, Pharmacokinetics, biotransformation, and mass balance of edoxaban, a selective, direct factor Xa inhibitor, in humans. Drug Metab Dispos. 2012 Dec;40(12):2250-5.

描述

Edoxaban(DU-176)是口服的FXa抑制剂,临床开发用于中风预防。

相关类别

信号通路 >> 代谢酶/蛋白酶 >> 因子Xa

研究领域 >> 心血管疾病

参考文献

[1]. Mendell J, Lee F, Chen S, The Effects of the Antiplatelet Agents, Aspirin and Naproxen, on Pharmacokinetics and Pharmacodynamics of the Anticoagulant Edoxaban, a Direct Factor Xa Inhibitor. J Cardiovasc Pharmacol. 2013 Apr 23. [Epub ahead of print]

[2]. Mendell J, Noveck RJ, Shi M. Pharmacokinetics of the direct factor Xa inhibitor edoxaban and digoxin administered alone and in combination. J Cardiovasc Pharmacol. 2012 Oct;60(4):335-41.

[3]. Bathala MS, Masumoto H, Oguma T, Pharmacokinetics, biotransformation, and mass balance of edoxaban, a selective, direct factor Xa inhibitor, in humans. Drug Metab Dispos. 2012 Dec;40(12):2250-5.

分子式	C₃₁H₃₈ClN₇O₇S₂
分子量	720.259
精确质量	719.196289
PSA	227.62000
LogP	4.40480
InChIKey	ZLFZITWZOYXXAW-QXXZOGQOSA-N
SMILES	CN1CCc2nc(C(=O)NC3CC(C(=O)N(C)C)CCC3NC(=O)C(=O)Nc3ccc(Cl)cn3)sc2C1.Cc1ccc(S(=O)(=O)O)cc1
储存条件	2-8℃

edoxaban monotosylate

[14C]-Edoxaban tosylate

Lixiana

Edoxaban (tosylate)

Edoxabantosylate

Ethanediamide, N-(5-chloro-2-pyridinyl)-N-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-, 4-methylbenzenesulfonat e (1:1)

edoxaban 4-toluenesulfonate

edoxaban p-toluenesulfonate

Edoxaban tosilate

Edoxaban TsOH

Edoxaban tosylate

Edoxaban