Setipiprant
更新时间：2022-02-11 10:02:05
| 常用名 | 2-(2-(1-萘甲酰基)-8-氟-1.2.3.4-四氢吡啶并[4,3-B]吲哚-5基)乙酸 | CAS号 | 866460-33-5 |
|---|---|---|---|
| 价格 | ￥需询单/1kg | 纯度 | 99.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： Setipiprant is an orally available, selective CRTH2 antagonist. CRTH2 is a G protein-coupled receptor for PGD2.IC50 value: 6.0 nMTarget: PGD2in vitro: Setipiprant is an orally available, selective CRTH2 (chemoattractant receptor-homologous molecule expressed on T helper [Th]-2 cells) antagonist. CRTH2 is a G protein-coupled receptor for prostaglandin (PGD2). PGD2 is produced by the mast cells and is a key mediator in various inflammatory diseases, including allergy and asthma. Binding of PGD2 to CRTH2, which are expressed on the surface of blood-borne cells, induces chemotaxis of Th2 cells, basophils, and eosinophils, and stimulates cytokine release from these cells. Thus, antagonism of CRTH2 receptors is considered to be a promising therapeutic target for various allergic diseases and asthma. 物理化学性质： CAS号：866460-33-5 常用中文名：2-(2-(1-萘甲酰基)-8-氟-1.2.3.4-四氢吡啶并[4,3-B]吲哚-5基)乙酸 常用英文名：Setipiprant 分子式：C24H19FN2O3 分子量：402.418 密度：1.4±0.1 g/cm3 沸点：690.4±55.0 °C at 760 mmHg 熔点：N/A 闪点：371.4±31.5 °C 储存条件：-20℃ |
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：Setipiprant (ACT-129968)
- 价格： ￥2368.9/100mg ￥778.9/25mg ￥需询单/1g ￥需询单/100g
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
- 上海阿摩尔生物科技有限公司
- 上海市 上海市 奉贤区
- 产品名：2-(2-(1-萘甲酰基)-8-氟-3,4-二氢-1H-吡啶并[4,3-b]吲哚-5(2H)-基)乙酸
- 价格： ￥需询单/100mg ￥需询单/1g ￥需询单/250mg ￥需询单/5mg
- 纯度：98.0%
- 备货期：需询单
- 联系人：王汐瑶
- 上海化源世纪贸易有限公司
- 上海市 上海市 普陀区
- 产品名：2-(2-(1-Naphthoyl)-8-fluoro-1,2,3,4-tetrahydropyrido[4,3-b]indol-5-yl)aceticacid
- 价格：
- 纯度：98.0%
- 备货期：10天
- 联系人：徐经理
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2-(2-(1-萘甲酰基)-8-氟-1.2.3.4-四氢吡啶并[4,3-B]吲哚-5基)乙酸生产厂家
参考价格：$172/10mM*1mLinDMSO