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Linocaine hydrochloride

更新时间:2022-04-25 15:44:37

常用名 盐酸利多卡因 CAS号 73-78-9
价格 ¥需询单/1kg 纯度 99.0%
备货期 15天 库存 询单
 产品详情(用途,包装等)
用途:
Lidocaine Hcl salt, an amide local anesthetic, has anti-inflammatory properties in vitro and in vivo, possibly due to an attenuation of pro-inflammatory cytokines, intracellular adhesion molecule-1 (ICAM-1), and reduction of neutrophils influx.Target: Lidocaine is a common local anesthetic and antiarrhythmic drug. Lidocaine is used topically to relieve itching, burning and pain from skin inflammations, injected as a dental anesthetic or as a local anesthetic for minor surgery. Lidocaine, the first amino amide–type local anesthetic, was first synthesized under the name xylocaine by Swedish chemist Nils Lofgren in 1943. His colleague Bengt Lundqvist performed the first injection anesthesia experiments on himself.Lidocaine is approximately 95% metabolized (dealkylated) in the liver by CYP3A4 to the pharmacologically-active metabolites monoethylglycinexylidide (MEGX) and then subsequently to the inactive glycine xylidide. MEGX has a longer half life than lidocaine but also is a less potent sodium channel blocker. The elimination half-life of lidocaine is approximately 90–120 minutes in most patients. This may be prolonged in patients with hepatic impairment (average 343 minutes) or congestive heart failure (average 136 minutes).
物理化学性质:
CAS号:73-78-9
常用中文名:盐酸利多卡因
常用英文名:Lidocaine hydrochloride
分子式:C14H23ClN2O
分子量:270.798
密度:N/A
沸点:350.8ºC at 760 mmHg
熔点:80-82°C
闪点:166ºC
储存条件:Refrigerator

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参考价格:$66/10mM*1mLinWater
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