AMXI-5001

更新时间：2024-07-17 15:06:25 采购访问：6次

常用名	AMXI-5001	CAS号	2170491-77-5
价格	$需询单/100mg $需询单/250mg $需询单/1g	纯度	98.0%
备货期	3天	库存	3
产品网页	https://www.dcchemicals.com/product_show-amxi-5001.html

产品详情（用途，包装等） AMXI-5001 (AMXI 5001) is a novel, highly potent, orally active dual PARP1/2 (IC50 5/0.05 nM) and microtubule polymerization inhibitor, inhibits intracellular PAR formation with IC50 of 7 nM.AMXI-5001 binds to the catalytic domain of human PARP1 and is a weak tankyrase inhibitor (800-fold lower than IC50 towards either PARP1 or PARP2 enzymes).AMXI-5001 inhibited tubulin polymerization in a dose-dependent manner.AMXI-5001 exhibited selective antitumor cytotoxicity across a wide variety of human cancer cells with much lower IC50s than existing clinical PARP1/2 inhibitors.AMXI-5001 is highly active in both BRCA mutated and wild type cancers.AMXI-5001 elicited a remarkable In vivo preclinical anti-tumor activity in a BRCA mutated TNBC model induced complete regression of established tumors, including exceedingly large tumors, demonstrated superior anti-tumor effects compared to either single agent (PARP or microtubule) inhibitor or combination with both agents.

DC Chemicals Limited

认证状态：已认证供应商
商品数：34963件
电话：58447131
地址：浦东新区金豫路100号
地区：上海市上海市浦东新区
联系人：Tony Cao
联系人电话：13564518121
邮件：sales@dcchemicals.com
网址：http://www.dcchemicals.com
主要市场：
年贸易额：>1000万
外贸占销售比例：
主要合作伙伴：

D&C Chemicals provides a wide range of research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and Natural compounds for laboratory and scientific use.

D&C Chem has established a global network of thousands of customers from many research centers and Reagent companies in the USA, Europe and Japan.

We are the the official vendor of more than 500 universities and institutes including: Harvard University,Yale University,NIH/NCI, City of Hope ORG, PARTNERS ORG,John Hopkins University,Universit tsklinikum,Oxford University,Newcastle University,UNC,UCSF and many other universities and institutes. Our bioactive compounds received good feedback from our customers.

Our credo is committed to the adoption of different products, reliable quality, competitive prices and quality service to create value for customers.

上海化源生化科技有限公司
上海市上海市普陀区
产品名：AMXI-5001
价格：
纯度：98.0%
备货期：10天
联系人：徐经理

上海阿拉丁生化科技股份有限公司
上海市上海市浦东新区
产品名：AMXI-5001
价格：￥4500.9/5mg ￥8000.9/10mg
纯度：98.0%
备货期：10天
联系人：阿拉丁

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AMXI-5001生产厂家

参考价格：￥6500/5 mg

2024-07-15	AMXI-5001 价格：需询单
2025-02-05	AMXI-5001 价格：￥4500.9

查看所有价格，请点击AMXI-5001价格