常用名 | PF 04937319,葡糖激酶部分激活剂 | CAS号 | 1245603-92-2 |
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价格 | ¥需询单/1g | 纯度 | 98.9% |
备货期 | 1天 | 库存 | 现货 |
产品详情(用途,包装等)
PF-04937319 is a glucokinase activator which is under development for the treatment of type 2 diametes mellitus. Glucose-phosphorylating enzyme, glucokinase (GK) plays a major role in glucose homeostasis primarily through its regulatory actions in pancreatic β-cells and liver hepatocytes. Conversion of glucose to glucose-6-phosphate by GK promotes glycogen synthesis in liver hepatocytes, and insulin release in the pancreatic β-cells. |