CGP 48664
更新时间：2024-01-13 22:46:54
| 常用名 | Sardomozide dihydrochloride | CAS号 | 138794-73-7 |
|---|---|---|---|
| 价格 | ￥需询单/1g | 纯度 | 98.9% |
| 备货期 | 1天 | 库存 | 现货 |
| 产品详情（用途，包装等）
Sardomozide HCl, also known as SAM486A or CGP48664, is a second-generation polyamine synthesis inhibitor, which inhibits the activity of the polyamine biosynthetic enzyme S-adenosylmethionine decarboxylase (SAMDC). SAM486 is more potent and specific than the first-generation SAMDC inhibitor methylglyoxal (bis) guanylhydrazone (MGBG). Preclinical testing confirmed promising antiproliferative activity. The in vitro tests showed that p53 wild-type NB cells were highly sensitive to SAM486A treatment. Most notably, SAM486A treatment resulted in the rapid accumulation of proapoptotic proteins p53 and Mdm2. |
- 上海化源世纪贸易有限公司
- 上海市 上海市 普陀区
- 产品名：2-(4-甲脒基-2,3-二氢-1H-茚-1-亚基)肼-1-甲脒基二盐酸盐
- 价格：
- 纯度：99.0%
- 备货期：10天
- 联系人：徐经理
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Sardomozide dihydrochloride生产厂家
参考价格：$140/5mg