常用名 | API-1 | CAS号 | 36707-00-3 |
---|---|---|---|
价格 | ¥需询单/1g | 纯度 | 98.9% |
备货期 | 1天 | 库存 | 现货 |
产品详情(用途,包装等)
API-1 is a potent Akt inhibitor, which induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis . API-1 rapidly and potently reduced the levels of Mcl-1 primarily in API-1-senstive lung cancer cell lines. Ectopic expression of Mcl-1 protected cells from induction of apoptosis by API-1. |