| 常用名 | RBC8 | CAS号 | 361185-42-4 |
|---|---|---|---|
| 价格 | ¥需询单/1g ¥需询单/5g | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: RBC8 is a novel small molecule inhibitor of Ral GTPase; has IC50 of 3.5 μM in H2122 cell and 3.4 μM in H358 cell.IC50 value:Target: Ral GTPase inhibitorRBC8 or BQU57 treatment showed no further inhibition of colony formation after Ral knockdown. RBC8 and BQU57 showed favorable properties that define good drug candidates. To test the effect of Ral inhibitors on xenograft tumor growth, nude mice were inoculated subcutaneously with H2122 human lung cancer cells and treated intraperitoneally with 50 mg/kg/d of RBC8 for 21 days (except weekends). RBC8 inhibited tumor growth to a similar extent as dual knockdown of RalA and RalB. 物理化学性质: CAS号:361185-42-4 常用中文名:RBC8 常用英文名:RBC8 分子式:C25H20N4O3 分子量:424.45100 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A 储存条件:-20℃ |