Y320
更新时间：2025-09-03 09:13:30
| 常用名 | Y型320 | CAS号 | 288250-47-5 |
|---|---|---|---|
| 价格 | ￥需询单/1kg ￥需询单/1g ￥需询单/1mg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： Y-320 is a new phenylpyrazoleanilide immunomodulator; inhibits IL-17 production by CD4 T cells stimulated with IL-15 with IC50 values of 20 to 60 nM.IC50 value: 20-60 nM (IL-17 production) [1]Target: IL-17Y-320 inhibited IL-17 production by CD4 T cells stimulated with IL-15 with IC50 values of 20 to 60 nM. Oral administration of Y-320 (0.3 to 3 mg/kg) significantly inhibited the development and progression of arthritis and joint destruction with reduction of IL-17 mRNA expression in arthritic joints of type II collagen-induced arthritis (CIA) in DBA/1J mice. Y-320 in combination with anti-murine tumor necrosis factor-α monoclonal antibody showed a synergistic effect on mouse CIA. Moreover, therapeutic treatment with Y-320 (0.3 and 1 mg/kg orally) ameliorated CIA in cynomolgus monkeys [1]. 物理化学性质： CAS号：288250-47-5 常用中文名：Y型320 常用英文名：Y-320 分子式：C27H29ClN6O2 分子量：505.011 密度：1.3±0.1 g/cm3 沸点：631.2±55.0 °C at 760 mmHg 熔点：N/A 闪点：335.6±31.5 °C 储存条件：-20℃ |
- 上海化源世纪贸易有限公司
- 上海市 上海市 普陀区
- 产品名：1-(4-氯苯基)-N-(3-氰基-4-(4-吗啉哌啶-1-基)苯基)-5-甲基-1H-吡唑-4-甲酰胺
- 价格：
- 纯度：98.0%
- 备货期：10天
- 联系人：徐经理
查看所有供应商和价格请点击：
参考价格：$133/10mM*1mLinDMSO