| 常用名 | (2S,5R)-5-(4-((2-氟苄基)氧基)苯基)吡咯烷-2-甲酰胺 | CAS号 | 934240-30-9 |
|---|---|---|---|
| 价格 | ¥需询单/1kg ¥需询单/1g ¥需询单/1mg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情(用途,包装等)
用途: CNV1014802(GSK-1014802) is a novel small molecule state-dependent sodium channel blocker; Nav1.7 sodium channel inhibitor.IC50 value: Target: sodium channel blockerLike lamotrigine, both GSK2 and GSK3 were able to prevent the deficit in reversal learning produced by PCP, thus confirming their potential in the treatment of cognitive symptoms of schizophrenia. However, higher doses than those required for anticonvulsant efficacy of the drugs were needed for activity in the reversal-learning model, suggesting a lower therapeutic window relative to mechanism-dependent central side effects for this indication. CNV1014802 received orphan-drug designation from the US Food and Drug Administration in July 2013. 物理化学性质: CAS号:934240-30-9 常用中文名:(2S,5R)-5-(4-((2-氟苄基)氧基)苯基)吡咯烷-2-甲酰胺 常用英文名:CNV1014802 分子式:C18H19FN2O2 分子量:314.35400 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A 储存条件:2-8°C,避光,保存于惰性气体中 |