LDN214117
更新时间：2024-09-07 15:06:40
| 常用名 | LDN-214117 | CAS号 | 1627503-67-6 |
|---|---|---|---|
| 价格 | ￥需询单/1kg ￥需询单/1g ￥需询单/1mg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： LDN-214117 is a potent and selective ALK2 inhibitor with IC50 of 22 nM; > 100 fold selectivity for ALK5; also inhibits BMP6(IC50=100 nM).IC50 value: 22 nM(ALK2) [1]Target: ALK2 inhibitorLDN-214117 is a highly BMP selective compound, significantly biased toward ALK2 and its cognate ligands including BMP6 and also demonstrates a high degree of kinome selectivity and lowcytotoxicity. LDN-214117 may be useful as highly selectiveprobes of BMP-mediated cellular physiology that may provide auseful complement to the dorsomorphin class of compounds. Furthermore, this class of BMP inhibitors offers a structurallydistinct template for the development of therapeutics for thetreatment of BMP signaling-mediated diseases such as FOP. 物理化学性质： CAS号：1627503-67-6 常用中文名：LDN-214117 常用英文名：LDN 214117 分子式：C25H29N3O3 分子量：419.516 密度：1.1±0.1 g/cm3 沸点：567.9±50.0 °C at 760 mmHg 熔点：N/A 闪点：297.3±30.1 °C 储存条件：2-8°C |
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：LDN 214117
- 价格： ￥657.9/5mg ￥4428.9/100mg ￥896.9/10mg ￥2059.9/25mg
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
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参考价格：$94/10mM*1mLinDMSO