| 常用名 | ONO-4059模拟 | CAS号 | 1351635-67-0 |
|---|---|---|---|
| 价格 | ¥需询单/1kg ¥需询单/1g ¥需询单/1mg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情(用途,包装等)
用途: The product is the analog of ONO-4059, ONO-4059 is a highly potent and selective Btk inhibitor with an IC50 in the sub-nM range. IC50 value: sub-nM range [2]Target: Btkin vitro: ONO-4059 ( analog ) is a selective, once-daily, oral inhibitor of BTK, which has been shown to play a role in the survival and proliferation of malignant B-cells. ONO-4059 (analog) shows a favourable safety profile along with promising efficacy in this difficult-to-treat patient population. [1]in vivo: ONO-4059 (analog) has demonstrated anti-tumour activity in several pre-clinical models.[1] ONO-4059 (analog) potently and dose-dependently reverse clinical arthritis and prevented bone damage in the CIA model.[2] 物理化学性质: CAS号:1351635-67-0 常用中文名:ONO-4059模拟 常用英文名:ONO-4059 (analog) 分子式:C25H24N6O3 分子量:456.496 密度:1.4±0.1 g/cm3 沸点:714.0±70.0 °C at 760 mmHg 熔点:N/A 闪点:385.6±35.7 °C 储存条件:-20℃ |