Roquinimex
更新时间：2025-09-16 18:29:04
| 常用名 | 利诺安 | CAS号 | 84088-42-6 |
|---|---|---|---|
| 价格 | ￥需询单/1mg ￥需询单/1g | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： Roquinimex (Linomide; PNU212616; ABR212616) is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis and reduces the secretion of TNF alpha.IC50 value:Target: TNF alphaProphylactic administration of DSS-treated mice with roquinimex significantly reduced clinical signs of colitis, MDS and the CH-reduction. Moreover, in roquinimex treated animals, the MPO activity was significantly reduced by more than 50% compared to DSS control mice. Notably, therapeutic administration of roquinimex in DSS-treated mice also significantly inhibited the MDS, CH-reduction and MPO activity [2]. Linomide, a synthetic immunomodulator, at concentrations effective in vivo reduces the number of MBP-reactive TNF-alpha and increases MBP-reactive IL-10 and TGF-beta mRNA expressing MNC from MS patients' blood when analysed in vitro. Compared to dexamethasone, Linomide up-regulated levels of blood MNC expressing mRNA of TGF-beta after culture in presence of MBP [3]. 物理化学性质： CAS号：84088-42-6 常用中文名：利诺安 常用英文名：Roquinimex 分子式：C18H16N2O3 分子量：308.331 密度：1.4±0.1 g/cm3 沸点：436.2±45.0 °C at 760 mmHg 熔点：204 °C(dec.) 闪点：217.6±28.7 °C 储存条件：室温 |
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：利诺安
- 价格： ￥262.9/10mg ￥1235.9/50mg ￥720.9/1ml ￥需询单/1g
- 纯度：96.0%
- 备货期：1天
- 联系人：阿拉丁
- 武汉敬康恩生物医药科技有限公司
- 湖北省 武汉市 东西湖区
- 产品名：Roquinimex
- 价格： ￥需询单/1g ￥需询单/5g
- 纯度：98.0%
- 备货期：需询单
- 联系人：周经理
查看所有供应商和价格请点击：
参考价格：$164/10mM*1mLinDMSO