| 常用名 | 那托西派 | CAS号 | 209219-38-5 |
|---|---|---|---|
| 价格 | ¥需询单/1mg | 纯度 | 98.0% |
| 备货期 | 1天 | 库存 | 询单 |
| 产品详情(用途,包装等)
用途: Nastorazepide (Z-360) is a selective, orally available, 1,5-benzodiazepine-derivative gastrin/cholecystokinin 2 (CCK-2) receptor antagonist with potential antineoplastic activity. Target:CCK-2in vitro: Z-360 binds to the gastrin/CCK-2 receptor, thereby preventing receptor activation by gastrin, a peptide hormone frequently associated with the proliferation of gastrointestinal and pancreatic tumor cells. Check for active clinical trials or closed clinical trials using this agent. in vivo: Z-360 is a novel orally active CCK-2/gastrin receptor antagonist, significantly inhibits the growth of subcutaneous xenografts of human pancreatic tumor cells in mice, and that Z-360 combined with gemcitabine prolonged survival in a pancreatic carcinoma orthotopic xenograft mice. 物理化学性质: CAS号:209219-38-5 常用中文名:那托西派 常用英文名:Nastorazepide 分子式:C29H36N4O5 分子量:520.620 密度:1.3±0.1 g/cm3 沸点:742.8±60.0 °C at 760 mmHg 熔点:N/A 闪点:403.0±32.9 °C 储存条件:2-8℃ |