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格隆溴铵,甘罗溴铵

更新时间:2025-09-23 13:18:55

常用名 甘罗溴铵 CAS号 596-51-0
价格 ¥需询单/1kg ¥需询单/1g 纯度 98.0%
备货期 3天 库存 现货
 产品详情(用途,包装等)
用途:
Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic.IC50 Value:Target: mAChR (Muscarinic acetylcholine receptor M1)in vitro: Glycopyrrolate showed no selectivity in its binding to the M1-M3 receptors. Kinetics studies, however, showed that glycopyrrolate dissociates slowly from HASM muscarinic receptors (60% protection against [3H]-NMS binding at 30 nM) compared to ipratropium bromide [1].in vivo: Glycopyrrolate (1 mg) tablets were then administered, starting with one tablet daily the third week and increasing the daily dose by one tablet per week until a maximum of four tablets during week six and 4 days of week seven when the daily dose was reduced to two tablets for 3 days. glycopyrrolate can be given in controlled doses provided that an adequate medical assessment has been undertaken [2]. Glycopyrrolate has a slow and erratic absorption from the gastrointestinal system, but even low plasma levels are associated with a distinct and long-lasting antisialogic effect [3]. Oral glycopyrrolate is emerging as a potential second-line treatment option, but experience with safety, efficacy, and dosing is especially limited in children [4]. phase III study, 52.3% of glycopyrrolate oral solution recipients (aged 3-18 years; n = 137) had an mTDS response (primary endpoint); the response rate was consistently above 50% at all 4-weekly timepoints, aside from the first assessment at week 4 (40.3%). In general, glycopyrrolate oral solution was well tolerated in clinical trials. The majority of adverse events were within expectations as characteristic anticholinergic outcomes [5].Toxicity: Side effects include dry mouth, difficult urinating, heachaches, diarrhea and constipation. The medication also induces drowsiness or blurred vision. LD50=709 mg/kg (rat, oral).
物理化学性质:
CAS号:596-51-0
常用中文名:甘罗溴铵
常用英文名:Glycopyrrolate
分子式:C19H28BrNO3
分子量:398.335
密度:N/A
沸点:N/A
熔点:193 - 194.5ºC
闪点:N/A
储存条件:Hygroscopic, -20°C Freezer, Under Inert Atmosphere

供应商信息

宝鸡凯维康生物科技有限公司

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宝鸡凯维康生物科技有限公司坐落于誉称“炎帝故里、青铜器之乡”的陕西省宝鸡市,从事天然食品添加剂、食用植物提取物的研究开发与生产。以及药用中间体、单体、药用保健品生产的高科技型企业。 凯维康确保所有产品的质量都符合GMP、ISO9001:2008及HACCP标准。 公司重视产品开发,在自行开发产品的同时也积极与国内的行业名厂、高校、实验室进行合作。公司拥有先进的纯水制备、提取、萃取、层析、浓缩、精制、真空干燥等生产设备拥有高效液相色谱仪(HPLC)等各种实验分析设备,严格进行生产管理,以确保出厂产品的质量。  本公司生产的白藜芦醇,石榴提取物,葡萄籽提取物,银杏叶提取物,人参提取物,越橘提取物,绿茶提取物,甜叶菊提取,沙棘提取物,冬虫夏草提取物,淫羊藿提取物,生姜提取物,葡萄籽提取物,山楂提取物,水飞蓟提取物,蘑菇提取物,藜豆提取物,橄榄叶提取物,石榴皮提取物,松树皮提取物,锯叶棕提取物,海带提取物,花青素,姜黄素,喜树碱,辅酶Q10,橙皮甙,五羟基色氨酸,淫羊藿甙,左旋肉碱,等余种产品,销往国内、港澳台、欧美和东南亚等国家和地区,已经成为国内外许多医药、食品、保健品、化妆品生产企业的首选产品。  公司拥有完整、科学的质量管理体系。宝鸡凯维康生物科技有限公司的诚信、实力和产品质量获得业界的认可。欢迎各界朋友莅临参观、指导和业务洽谈。
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参考价格:$66/10mM*1mLinWater
其他供应商价格:
2024-07-15 格隆溴铵
价格:需询单
2019-03-05 甘罗溴铵
价格:¥5378.0
2022-11-29 Glycopyrrolate
价格:¥需询单
2021-02-06 Glycopyrrolate
价格:¥489.0
2025-09-17 3-(2-环戊基-2-羟基-2-苯基乙酰氧基)-1,1-二甲基吡咯烷-1-嗡溴化物
价格:¥需询单
2022-02-19 甘罗溴铵
价格:¥47.9
2023-11-18 Glycopyrrolate
价格:¥需询单
2024-09-13 格隆溴铵
价格:¥需询单
2018-02-07 Glycopyrrolate
价格:¥需询单
2022-05-27 格隆溴铵
价格:¥1000.0

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