Glycopyrrolate
更新时间：2025-09-01 12:36:10
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| 常用名 | 甘罗溴铵 | CAS号 | 596-51-0 |
|---|---|---|---|
| 价格 | ￥需询单/1g | 纯度 | 98.0% |
| 备货期 | 1天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic.IC50 Value:Target: mAChR (Muscarinic acetylcholine receptor M1)in vitro: Glycopyrrolate showed no selectivity in its binding to the M1-M3 receptors. Kinetics studies, however, showed that glycopyrrolate dissociates slowly from HASM muscarinic receptors (60% protection against [3H]-NMS binding at 30 nM) compared to ipratropium bromide [1].in vivo: Glycopyrrolate (1 mg) tablets were then administered, starting with one tablet daily the third week and increasing the daily dose by one tablet per week until a maximum of four tablets during week six and 4 days of week seven when the daily dose was reduced to two tablets for 3 days. glycopyrrolate can be given in controlled doses provided that an adequate medical assessment has been undertaken [2]. Glycopyrrolate has a slow and erratic absorption from the gastrointestinal system, but even low plasma levels are associated with a distinct and long-lasting antisialogic effect [3]. Oral glycopyrrolate is emerging as a potential second-line treatment option, but experience with safety, efficacy, and dosing is especially limited in children [4]. phase III study, 52.3% of glycopyrrolate oral solution recipients (aged 3-18 years; n = 137) had an mTDS response (primary endpoint); the response rate was consistently above 50% at all 4-weekly timepoints, aside from the first assessment at week 4 (40.3%). In general, glycopyrrolate oral solution was well tolerated in clinical trials. The majority of adverse events were within expectations as characteristic anticholinergic outcomes [5].Toxicity: Side effects include dry mouth, difficult urinating, heachaches, diarrhea and constipation. The medication also induces drowsiness or blurred vision. LD50=709 mg/kg (rat, oral). 物理化学性质： CAS号：596-51-0 常用中文名：甘罗溴铵 常用英文名：Glycopyrrolate 分子式：C19H28BrNO3 分子量：398.335 密度：N/A 沸点：N/A 熔点：193 - 194.5ºC 闪点：N/A 储存条件：Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
武汉敬康恩生物医药科技有限公司
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- 上海化源生化科技有限公司
- 上海市 上海市 普陀区
- 产品名：格隆溴铵
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- 纯度：98.0%
- 备货期：10天
- 联系人：化源网
- 上海吉至生化科技有限公司
- 上海市 上海市 奉贤区
- 产品名：甘罗溴铵
- 价格： ￥5378.0/500mg ￥328.0/25mg ￥758.0/100mg
- 纯度：98.0%
- 备货期：需询单
- 联系人：刘佳
- 上海源溪生物科技有限公司
- 上海市 上海市 浦东新区
- 产品名：Glycopyrrolate
- 价格： ￥需询单/1g
- 纯度：98.9%
- 备货期：1天
- 联系人：赖经理
- 上海脉铂医药科技有限公司
- 上海市 上海市 嘉定区
- 产品名：Glycopyrrolate
- 价格： ￥489.0/1g ￥789.0/25mg ￥389.0/10mg ￥需询单/1g
- 纯度：98.0%
- 备货期：2天
- 联系人：李先生
- 上海阿摩尔生物科技有限公司
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- 产品名：3-(2-环戊基-2-羟基-2-苯基乙酰氧基)-1,1-二甲基吡咯烷-1-嗡溴化物
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- 上海阿拉丁生化科技股份有限公司
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- 产品名：甘罗溴铵
- 价格： ￥47.9/25mg ￥308.9/1ml ￥261.9/100mg ￥525.9/500mg
- 纯度：98.0%
- 备货期：1天
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- 武汉敬康恩生物医药科技有限公司
- 湖北省 武汉市 东西湖区
- 产品名：Glycopyrrolate
- 价格： ￥需询单/1g
- 纯度：98.0%
- 备货期：1天
- 联系人：周经理
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参考价格：$66/10mM*1mLinWater