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顺式-2-(氨基甲基)-N,N-二乙基-1-苯基环丙烷甲酰胺盐酸盐

更新时间:2024-07-15 12:29:41 采购访问:14次

常用名 盐酸米那普仑 CAS号 101152-94-7
价格 纯度 99.0%
备货期 10天 库存 现货
 产品详情(用途,包装等)
用途:
Milnacipran hydrochloride is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia.Target: SNRIMilnacipran (Ixel, Savella, Dalcipran, Toledomin) is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia. It is not approved for the clinical treatment of major depressive disorder in the USA, but it is in other countries.Milnacipran inhibits the reuptake of serotonin and norepinephrine in an approximately 1:3 ratio, respectively; in practical use this means a relatively balanced action upon bothneurotransmitters. Increasing both neurotransmitters concentration simultaneously works synergistically to treat both depression and fibromyalgia. Milnacipran exerts no significant actions onH1, α1, D1, D2, and mACh receptors, as well as on benzodiazepine and opioid binding sites. Milnacipran is well absorbed after oral dosing and has a bioavailability of 85%. Meals do not have an influence on the rapidity and extent of absorption. Peak plasma concentrations are reached 2 hours after oral dosing. The elimination half-life of 8 hours is not increased by liver impairment and old age, but by significant renal disease. Milnacipran is conjugated to the inactive glucuronide and excreted in the urine as unchanged drug and conjugate. Only traces of active metabolites are found.
物理化学性质:
CAS号:101152-94-7
常用中文名:盐酸米那普仑
常用英文名:Milnacipran hydrochloride
分子式:C15H23ClN2O
分子量:282.809
密度:N/A
沸点:393ºC at 760 mmHg
熔点:179-181ºC
闪点:N/A
储存条件:2-8°C

供应商信息

上海念兴实业有限公司 认证供应商

认证状态:已认证供应商
商品数:403768件
电话:18916513247
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地区: 上海市 上海市 普陀区
联系人:小陈
联系人电话:0086-021-52280163
邮件:sales@echemcloud.com
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参考价格:$75/10mM*1mLinDMSO
其他供应商价格:
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2024-01-09 Milnacipran Hydrochloride
价格:$需询单

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