利塞膦酸
更新时间：2024-07-15 12:29:56
采购访问：34次
| 常用名 | 利塞膦酸 | CAS号 | 105462-24-6 |
|---|---|---|---|
| 价格 | 纯度 | 99.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： Risedronic acid (Risedronate ) is a pyridinyl biphosphonate which inhibits osteoclast-mediated bone resorption.Target: OthersRisedronate, which was promoted in Croatia a few months ago, is the latest (III) generation of bisphosphonates, the most efficient anti-resorption drugs that inhibit osteoclast-mediated bone resorption and change the bone metabolism. Risedronate is hence the first line of bisphosphonates for the reduction of vertebral and non-vertebral fracture risks in postmenopausal women with osteoporosis or those with a high risk of osteoporosis. It also efficiently prevents bone loss or improves bone density in men and women on a long-term corticosteroid therapy .The administration of 20 and 25 mg/kg risedronate for 4 days led to decreases of parasitemia of 68.9% and 83.6%, respectively. On the seventh day of treatment the inhibitions were 63% and 88.9% with 20 and 25 mg/kg, respectively. After recovering the parasitemia, a dose-response curve was obtained for estimating the ID50 (dose causing 50% inhibition), equivalent to 17 ± 1.8 mg/kg after 7 days of treatment. Four days after the interruption of treatment (11 days postinfection), the parasitemias of the groups treated with 10, 15, 20, and 25 mg/kg/day were 15.3%, 15.9%, 15.2%, and 5.7%, respectively. Conversely, the group that received PBS presented parasitemia of 25.6%. Among the groups treated with risedronate, only the animals that received 25 mg/kg had a significant inhibition of 77.8% (see Table S1 in the supplemental material), demonstrating that even after treatment discontinuation, the parasitemia of the animals remained low in relation to that of the controls . 物理化学性质： CAS号：105462-24-6 常用中文名：利塞膦酸 常用英文名：Risedronic acid 分子式：C7H11NO7P2 分子量：283.112 密度：1.9±0.1 g/cm3 沸点：692.3±65.0 °C at 760 mmHg 熔点：N/A 闪点：372.5±34.3 °C 储存条件：2~8°C |
上海念兴实业有限公司
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- 上海化源生化科技有限公司
- 上海市 上海市 普陀区
- 产品名：利塞膦酸
- 价格：
- 纯度：99.0%
- 备货期：10天
- 联系人：化源网
- 上海吉至生化科技有限公司
- 上海市 上海市 奉贤区
- 产品名：利塞膦酸
- 价格： ￥408.0/5g ￥1128.0/25g
- 纯度：99.0%
- 备货期：3天
- 联系人：刘佳
- 上海源溪生物科技有限公司
- 上海市 上海市 浦东新区
- 产品名：Risedronic acid (Actonel)
- 价格： ￥需询单/1g
- 纯度：98.9%
- 备货期：1天
- 联系人：赖经理
- 上海脉铂医药科技有限公司
- 上海市 上海市 嘉定区
- 产品名：Risedronate
- 价格： ￥789.0/100mg ￥2389.0/500mg ￥3589.0/1g ￥需询单/1g
- 纯度：98.0%
- 备货期：2天
- 联系人：李先生
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：利塞膦酸
- 价格： ￥141.0/5g ￥471.0/25g ￥46.0/1g ￥需询单/1g
- 纯度：99.0%
- 备货期：1天
- 联系人：阿拉丁
- 盼得（上海）国际贸易有限公司
- 上海市 上海市 徐汇区
- 产品名：利塞膦酸
- 价格： ￥需询单/500g ￥需询单/1kg ￥需询单/25kg ￥需询单/200kg
- 纯度：0.0%
- 备货期：需询单
- 联系人：叶经理
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参考价格：$86/100mg