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红霉素

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常用名 红霉素 CAS号 114-07-8
价格 纯度 98.0%
备货期 10天 库存 现货
 产品详情(用途,包装等)
用途:
Erythromycin, an oral macrolide antibiotic produced by Streptomyces erythreus, reversibly binds to the 50S ribosome of bacteria, and inhibits protein synthesis.Target: AntibacterialErythromycin is a macrolide antibiotic that has an antimicrobial spectrum similar to or slightly wider than that of penicillin, and is often prescribed for people who have an allergy to penicillins. For respiratory tract infections, it has better coverage of atypical organisms, including Mycoplasma and legionellosis. It was first marketed by Eli Lilly and Company, and it is today commonly known as EES (erythromycin ethylsuccinate, an ester prodrug that is commonly administered). It is also occasionally used as a prokinetic agent.Erythromycin estolate has been associated with reversible hepatotoxicity in pregnant women in the form of elevated serum glutamic-oxaloacetic transaminase and is not recommended during pregnancy. Some evidence suggests similar hepatotoxicity in other populations. Erythromycin displays bacteriostatic activity or inhibits growth of bacteria, especially at higher concentrations, but the mechanism is not fully understood. By binding to the 50s subunit of the bacterial 70s rRNA complex, protein synthesis and subsequent structure and function processes critical for life or replication are inhibited. Erythromycin interferes with aminoacyl translocation, preventing the transfer of the tRNA bound at the A site of the rRNA complex to the P site of the rRNA complex. Without this translocation, the A site remains occupied and, thus, the addition of an incoming tRNA and its attached amino acid to the nascent polypeptide chain is inhibited. This interferes with the production of functionally useful proteins, which is the basis of this antimicrobial action.
物理化学性质:
CAS号:114-07-8
常用中文名:红霉素
常用英文名:Erythromycin
分子式:C37H67NO13
分子量:733.927
密度:1.2±0.1 g/cm3
沸点:818.4±65.0 °C at 760 mmHg
熔点:138-140ºC
闪点:448.8±34.3 °C
储存条件:存放于惰性气体之中;避免湿气 (吸湿)

供应商信息

上海念兴实业有限公司 认证供应商

认证状态:已认证供应商
商品数:403768件
电话:18916513247
地址:2222 Huancheng Road, Juyuan New District, Jiading District, Shanghai
地区: 上海市 上海市 普陀区
联系人:小陈
联系人电话:0086-021-52280163
邮件:sales@echemcloud.com
网址:http://www.echemcloud.com
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参考价格:$66/10mM*1mLinDMSO
其他供应商价格:
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2018-10-24 红霉素 114-07-8 现货
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2017-12-11 红霉素
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2018-08-06 红霉素
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