| 常用名 | LMT-28 | CAS号 | 1239600-18-0 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: LMT-28 (LMT28) is a specific blocker of IL-6 signaling via inhibits IL-6Rβ (gp130) with IC50 of 5.9 uM (IL-6–induced luciferase activity), selectively inhibits IL-6–induced phosphorylation of STAT3, JAK2, and gp130; does not affect LIF-induced STAT3 activation and not inhibit IL-11 stimulation on HepG2 cells; binds directly and specifically to gp130, and thereby inhibits the interaction of gp130 with the IL-6/IL-6Rα complex; inhibits IL-6–induced proliferation of the human erythroleukemic cell line TF-1 with IC50 of 7.5 uM; inhibits IL-6–induced TNF-α production, ameliorates the progression of pancreatitis in mice. 物理化学性质: CAS号:1239600-18-0 常用中文名:LMT-28 常用英文名:LMT-28 分子式:C17H29NO4 分子量:311.417 密度:1.1±0.1 g/cm3 沸点:452.9±38.0 °C at 760 mmHg 熔点:N/A 闪点:227.7±26.8 °C 储存条件:-20°C |