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福多斯坦

更新时间:2024-07-15 12:31:25 采购访问:15次

常用名 福多司坦 CAS号 13189-98-5
价格 纯度 98.0%
备货期 10天 库存 现货
 产品详情(用途,包装等)
用途:
Fudosteine is a novel mucoactive agent and a MUC5AC mucin hypersecretion inhibitor.Target: OthersFudosteine is a cysteine derivative that is used as an expectorant in chronic bronchial inflammatory disorders. The administration of fudosteine during the challenge with ovalbumin prevented the development of airway hyperresponsiveness and accumulation of lymphocytes in the airways. Eotaxin, IL-4, and TGF-β levels and the relative intensity of matrix metalloproteinase-2 and matrix metalloproteinase-9 (MMP-2 and MMP-9) in BAL fluid were reduced by the fudosteine treatment; however, the number of eosinophils in BAL fluid and serum IgE levels did not change. The expression of TGF-β, the development of goblet cell hyperplasia, subepithelial collagenization, and basement membrane thickening were also reduced by the fudosteine treatment [1]. Fudosteine inhibits MUC5AC mucin hypersecretion by reducing MUC5AC gene expression and the effects of fudosteine are associated with the inhibition of extracellular signal-related kinase and p38 mitogen-activated protein kinase in vivo and extracellular signal-related kinase in vitro [2].
作用:
1.气道黏液过度分泌作用的抑制机制,抑制杯状细胞过度形成。
2.黏液修复作用。
3.浆液性气道分泌亢进作用。
4.抗炎症作用。
物理化学性质:
CAS号:13189-98-5
常用中文名:福多司坦
常用英文名:Fudosteine
分子式:C6H13NO3S
分子量:179.237
密度:1.3±0.1 g/cm3
沸点:354.5±42.0 °C at 760 mmHg
熔点:210.9-212.5ºC
闪点:168.2±27.9 °C
储存条件:-20°C Freezer
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供应商信息

上海念兴实业有限公司 认证供应商

认证状态:已认证供应商
商品数:403768件
电话:18916513247
地址:2222 Huancheng Road, Juyuan New District, Jiading District, Shanghai
地区: 上海市 上海市 普陀区
联系人:小陈
联系人电话:0086-021-52280163
邮件:sales@echemcloud.com
网址:http://www.echemcloud.com
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参考价格:¥210.6/50mg
其他供应商价格:
2022-02-19 Fudosteine
价格:¥104.9
2018-05-13 福多司坦
价格:¥需询单
2017-06-12 福多司坦
价格:¥需询单
2017-09-11 福多司坦
价格:¥需询单
2022-09-20 福多司坦
价格:¥56.0
2023-09-06 福多司坦
价格:¥430.0
2018-03-30 Fudosteine
价格:$400.0
2018-12-27 福多司坦
价格:¥需询单
2021-02-06 Fudosteine
价格:¥639.0

查看所有价格,请点击福多司坦价格