CBB1007?
更新时间：2024-07-15 12:31:49
采购访问：10次
| 常用名 | CBB1007 | CAS号 | 1379573-92-8 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： CBB1007 is a cell-permeable amidino-guanidinium compound that acts as a potent, reversible and substrate competitive LSD1 selective inhibitor (IC50 = 5.27 μM for hLSD1).IC50 Value: 5.27 uMTarget: hLSD1CBB1007 efficiently can block LSD1-mediated demethylation of H3K4Me2 and H3K4Me (IC50 ≤ 5 μM) with no effect on H3K4Me3 and H3K9Me2, and LSD2 and JARID1A activities. Increases H3K4Me2 and H3K4Me contents (IC50 ≤ 5 μM), and causes activation of epigenetically suppressed CHRM4/M4-ArchR and SCN3A genes in F9 cells (IC50 ≤ 3.74 μM). CBB1007 was Shown to preferentially arrest the growth of pluripotent tumors with minimal effect on non-pluripotent cancer or normal somatic cells (IC50 ≥ 100 μM). 物理化学性质： CAS号：1379573-92-8 常用中文名：CBB1007 常用英文名：CBB1007 分子式：C27H34N8O4 分子量：534.610 密度：1.4±0.1 g/cm3 沸点：763.8±70.0 °C at 760 mmHg 熔点：N/A 闪点：415.7±35.7 °C 储存条件：2-8℃ |
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