| 常用名 | GS-493 | CAS号 | 1710337-31-7 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: GS-493 is a novel potent, selective SHP2 inhibitor with IC50 of 71±15 nM in enzyme assay; displays 29- and 45-fold selectivity against related SHP1 and PTP1B; blocks HGF-stimulated epithelial-mesenchymal transition of human pancreatic adenocarcinoma (HPAF) cells, and inhibits cell colony formation in the NSCLC cell line LXFA 526L in soft agar; inhibits tumor growth in murine xenograft model. 物理化学性质: CAS号:1710337-31-7 常用中文名:GS-493 常用英文名:GS-493 分子式:C21H14N6O8S 分子量:510.437 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A 储存条件:-20°C,干燥,密封 |