| 常用名 | KY-02327 | CAS号 | 2093407-25-9 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: KY-02327 is an orally active, small molecule inhibitor of the Dishevelled (Dvl)-CXXC5 interaction with IC50 of 3.1 uM, a metabolically stabilized KY-02061 analog; KY-02327 is more stable by 2.3-fold and 1.3-fold than KY-02061 in rat liver microsomes and in human hepatocytes, respectively; shows enhanced effect on induction of ALP activity of osteoblast cells compared with KY-02061; activates the Wnt/β-catenin pathway, promotes osteoblast differentiation, and rescues BMD, bone volume, and trabecular bone structures in variectomized (OVX) mouse model. 物理化学性质: CAS号:2093407-25-9 常用中文名:KY-02327 常用英文名:KY-02327 分子式:C20H27N3O4 分子量:373.453 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A 储存条件:-20°C |