化合物CU-CPD107
更新时间：2026-01-30 17:31:47
采购访问：6次
| 常用名 | CU-CPD107 | CAS号 | 2573912-32-8 |
|---|---|---|---|
| 价格 | 纯度 | 98.86% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： CU-CPD107 is a TLR8-specific small molecule with unique synergistic agonist activities in the presence of ssRNA, but inactive without the aid of ssRNA.CU-CPD107 significantly inhibited of R848-induced signaling in HEK-Blue hTLR8 cells with an IC50 of 13.7 uM.CU-CPD107 only inhibited synthesized small-molecule agonist-induced TLR8 signaling without affecting other TLRs.CU-CPD107 synergistically increased IFN-β, TNF-α, IL-1β, IL-6, and IL-8 mRNA expression levels in the presence of 5 μg/ml ssRNA40 in HEK-Blue hTLR8 cells, whereas CU-CPD107 alone did not. CU-CPD107 only activated TLR8-mediated signaling in the presence of ssRNA.CU-CPD107 showed no pure agonistic activity, addressing a major challenge that has existed for previous TLR7 and TLR8 agonists as vaccine adjuvants or antiviral drugs. 物理化学性质： CAS号：2573912-32-8 常用中文名：CU-CPD107 常用英文名：CU-CPD107 分子式：C16H21In2O2 分子量：400.26 密度：N/A 沸点：N/A 熔点：N/A 闪点：N/A |
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