| 常用名 | ADS032 | CAS号 | 2757333-37-0 |
|---|---|---|---|
| 价格 | 纯度 | 99.33% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: ADS032 is a dual inhibitor of NLRP1 and NLRP3 that can rapidly, reversibly and stably inhibit inflammasome formation. ADS032 can reduce NLPR1 and NLRP3 activation of human macrophages and bronchial epithelial cells to secrete and mature IL-1β and TNF-α, and reduce NLRP3-induced ASC speck formation. ADS032 protected mice against the deadly influenza A virus, reducing inflammation in the lungs and improving survival. ADS032 inhibits Nigericin (HY-127019)-induced IL-1β secretion with IC50s of 94.6 μM (No wash out) and 354 μM (Wash out) respectively[1]. 物理化学性质: CAS号:2757333-37-0 常用中文名:ADS032 常用英文名:ADS032 分子式:C22H29NO4S 分子量:403.53 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |