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化合物 ADS032

更新时间:2024-07-15 12:34:23 采购访问:10次

常用名 ADS032 CAS号 2757333-37-0
价格 纯度 99.33%
备货期 10天 库存 现货
 产品详情(用途,包装等)
用途:
ADS032 is a dual inhibitor of NLRP1 and NLRP3 that can rapidly, reversibly and stably inhibit inflammasome formation. ADS032 can reduce NLPR1 and NLRP3 activation of human macrophages and bronchial epithelial cells to secrete and mature IL-1β and TNF-α, and reduce NLRP3-induced ASC speck formation. ADS032 protected mice against the deadly influenza A virus, reducing inflammation in the lungs and improving survival. ADS032 inhibits Nigericin (HY-127019)-induced IL-1β secretion with IC50s of 94.6 μM (No wash out) and 354 μM (Wash out) respectively[1].
物理化学性质:
CAS号:2757333-37-0
常用中文名:ADS032
常用英文名:ADS032
分子式:C22H29NO4S
分子量:403.53
密度:N/A
沸点:N/A
熔点:N/A
闪点:N/A

供应商信息

上海念兴实业有限公司 认证供应商

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