| 常用名 | L-685458 | CAS号 | 292632-98-5 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: L-685458 is a potent inhibitor of Amyloid β-Protein precursor γ-secretase activity with IC50 of 17 nM, shows greater than 50-100-fold selectivity over other aspartyl proteases tested.IC50 value: 17 nMTarget: γ-secretasein vitro: L-685458 is a Notch inhibitor. L-685458 blocks Notch activation in the two cell lines in terms of reduced cytoplasmic distribution and almost diminished nuclear labelling of Hes1 proteins. [2] L-685458 is a γ-secretase inhibitor. [3] 物理化学性质: CAS号:292632-98-5 常用中文名:L-685458 常用英文名:L-685,458 分子式:C39H52N4O6 分子量:672.85300 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A 储存条件:-20℃ |